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| 產(chǎn)地 | 北京 |
| 品牌 | solarbio |
| 保存條件 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 貨號(hào) | K000007M |
| 應(yīng)用范圍 | WB,IP |
| CAS編號(hào) | |
| 抗體名 | Anti-Dynactin 1(N-term) Monoclonal Antibody |
| 克隆性 | |
| 靶點(diǎn) | 1支/50μl/960RMB |
| 適應(yīng)物種 | Human |
| 形態(tài) | Lyophilized or Liquid |
| 宿主 | Mouse |
| 亞型 | IgG1 |
| 標(biāo)識(shí)物 | |
| 濃度 | % |
| 免疫原 | Purified recombinant Dynactin 1 protein fragments expressed in E.coli |
| 英文名稱 | Mouse Dynactin 1(N-term) Monoclonal Antibody |
|---|---|
| 應(yīng)用2 | WB IP |
| 克隆類型2 | Monoclonal Antibody |
| 別名 | Dynactin 1(N-term) |
| 應(yīng)用 | WB,IP |
| 稀釋比例 | WB1:500 |
| 交叉反應(yīng) | Human |
| 蛋白分子量 | 150kDa |
| Gene ID | 1639 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 儲(chǔ)存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 58% Glycerol. |
| 純化方法 | Affinity purification |
| 亞型 | IgG2b |
| 免疫原 | Purified recombinant Dynactin 1 protein fragments expressed in E.coli |
| 性狀 | Lyophilized or Liquid |
| Swiss Prot | Q14203 |
| 克隆號(hào) | 3D5-C6-D5 |
| 克隆類型 | Monoclonal Antibody |
| 來(lái)源 | Mouse |
| 背景資料 | This gene encodes the largest subunit of dynactin,a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kD.Dynactin binds to both microtubules and cytoplasmic dynein.Dynactin is involved in a diverse array of cellular functions,including ER-to-Golgi transport,the centripetal movement of lysosomes and endosomes,spindle formation,chromosome movement,nuclear positioning, and axonogenesis.This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus.Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).[provided by RefSeq, Oct 2008] |
