| 英文名稱 | Rabbit INSR Polyclonal Antibody |
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| 應(yīng)用2 | WB IHC |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | CD220;HHF5
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| 應(yīng)用 | WB,IHC |
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| 稀釋比例 | WB1:500-1:2000 IHC1:50-1:100 |
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| 交叉反應(yīng) | Human Mouse Rat |
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| 蛋白分子量 | 156kDa |
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| Gene ID | 3643 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲(chǔ)存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | A synthetic peptide of human INSR |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | P06213 |
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| 克隆類型 | Polyclonal Antibody |
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| 來(lái)源 | Rabbit |
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| 背景資料 | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. |
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