| 英文名稱 | Rabbit MGMT Polyclonal Antibody |
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| 應(yīng)用2 | WB IHC IF |
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| 克隆類型2 | Polyclonal Antibody |
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| 別名 | MGMT
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| 應(yīng)用 | WB,IHC,IF |
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| 稀釋比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:200 |
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| 交叉反應(yīng) | Human Mouse Rat |
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| 蛋白分子量 | 22kDa |
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| Gene ID | 4255 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
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| 儲存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | Recombinant protein of human MGMT |
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| 性狀 | Lyophilized or Liquid |
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| Swiss Prot | P16455 |
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| 克隆類型 | Polyclonal Antibody |
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| 來源 | Rabbit |
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| 背景資料 | Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. |
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