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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-CASP3 Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號:K101291P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-08-29
產(chǎn)品詳請
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K101291P
應(yīng)用范圍 WB IHC
CAS編號
抗體名 Anti-CASP3 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點 GSK3 alpha
適應(yīng)物種 Human Mouse
形態(tài)
宿主 Rabbit
亞型 IgG
標(biāo)識物 CPP32;CPP32B;SCA-1;SREBP cleavage activity 1;Cysteine protease CPP32
濃度 %
免疫原 A synthetic peptide of human CASP3
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
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