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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-ITA2B Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號:K106413P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-08-28
產(chǎn)品詳請
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K106413P
應(yīng)用范圍 WB
CAS編號
抗體名 Anti-ITA2B Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點 MKP1
適應(yīng)物種 Human
形態(tài)
宿主 Rabbit
亞型 IgG
標識物 ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93
濃度 %
免疫原 A synthetic peptide of human ITA2B
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
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