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北京索萊寶科技有限公司
產(chǎn)品展廳
Anti-NSMCE2 Polyclonal Antibody
  • 品牌:Solarbio
  • 產(chǎn)地:北京
  • 貨號:K106963P
  • 發(fā)布日期: 2019-05-13
  • 更新日期: 2025-08-22
產(chǎn)品詳請
產(chǎn)地 北京
品牌 Solarbio
保存條件 Store at -20°C. Avoid freeze / thaw cycles.
貨號 K106963P
應用范圍 WB
CAS編號
抗體名 Anti-NSMCE2 Polyclonal Antibody
克隆性 Polyclonal Antibody
靶點
適應物種 Human
形態(tài)
宿主 Rabbit
亞型 IgG
標識物 C8orf36;E3 SUMO protein ligase NSE2;hMMS21;MMS21;MMS21 homolog;Non SMC element 2 homolog;NSE2;NSMCE2
濃度 %
免疫原 Recombinant protein of human NSMCE2
This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.?
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