Anti-TrkA Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-08-22
產(chǎn)品詳請
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號 |
K107134P
|
應(yīng)用范圍 |
WB
|
CAS編號 |
|
抗體名 |
Anti-TrkA Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點 |
|
適應(yīng)物種 |
Human Mouse Rat
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識物 |
NTRK1;MTC;TRK;TRK1;TRKA;Trk-A;p140-TrkA;neurotrophic receptor tyrosine kinase 1
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human TrkA
|
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.