Anti-NRAS Polyclonal Antibody
- 發(fā)布日期: 2019-05-13
- 更新日期: 2025-05-12
產(chǎn)品詳請(qǐng)
產(chǎn)地 |
北京
|
品牌 |
Solarbio
|
保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
貨號(hào) |
K107233P
|
應(yīng)用范圍 |
WB
|
CAS編號(hào) |
|
抗體名 |
Anti-NRAS Polyclonal Antibody
|
克隆性 |
Polyclonal Antibody
|
靶點(diǎn) |
|
適應(yīng)物種 |
Human Mouse Rat Pig
|
形態(tài) |
|
宿主 |
Rabbit
|
亞型 |
IgG
|
標(biāo)識(shí)物 |
ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6
|
濃度 |
%
|
免疫原 |
A synthetic peptide of human NRAS
|
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.